A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency

TET1 maintains hypomethylation at bivalent promoters through its catalytic activity in embryonic stem cells (ESCs). However, TET1 catalytic activity-independent function in regulating bivalent genes is not well understood. Using a proteomics approach, we map the TET1 interactome in ESCs and identify...

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Detalles Bibliográficos
Autores principales: Huang, Xin, Bashkenova, Nazym, Hong, Yantao, Lyu, Cong, Guallar, Diana, Hu, Zhe, Malik, Vikas, Li, Dan, Wang, Hailin, Shen, Xiaohua, Zhou, Hongwei, Wang, Jianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214724/
https://www.ncbi.nlm.nih.gov/pubmed/35675764
http://dx.doi.org/10.1016/j.celrep.2022.110928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214724/
https://www.ncbi.nlm.nih.gov/pubmed/35675764
http://dx.doi.org/10.1016/j.celrep.2022.110928

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