Polycationic peptide R(7)-G-Aβ(25-35) selectively induces cell death in leukemia Jurkat T cells through speedy mitochondrial depolarization, and CASPASE-3 -independent mechanism

BACKGROUND: Acute lymphoblastic leukemia (ALL) is still incurable hematologic neoplasia in an important percentage of patients. Therefore, new therapeutic approaches need to be developed. METHODS: To evaluate the cellular effect of cell-penetrating peptides (C-PP) on leukemia cells, Jurkat cells -a...

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Detalles Bibliográficos
Autores principales: Mendivil-Perez, Miguel, Jimenez-Del-Rio, Marlene, Velez-Pardo, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214795/
https://www.ncbi.nlm.nih.gov/pubmed/35755270
http://dx.doi.org/10.1016/j.bbrep.2022.101300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214795/
https://www.ncbi.nlm.nih.gov/pubmed/35755270
http://dx.doi.org/10.1016/j.bbrep.2022.101300

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