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Development of a three-dimensional blood-brain barrier network with opening capillary structures for drug transport screening assays

The blood-brain barrier (BBB), a selective barrier regulating the active and passive transport of solutes in the extracellular fluid of the central nervous system, prevents the delivery of therapeutics for brain disorders. The BBB is composed of brain microvascular endothelial cells (BMEC), pericyte...

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Detalles Bibliográficos
Autores principales: Piantino, Marie, Kang, Dong-Hee, Furihata, Tomomi, Nakatani, Noriyuki, Kitamura, Kimiko, Shigemoto-Mogami, Yukari, Sato, Kaoru, Matsusaki, Michiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214798/
https://www.ncbi.nlm.nih.gov/pubmed/35757028
http://dx.doi.org/10.1016/j.mtbio.2022.100324