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Development of a three-dimensional blood-brain barrier network with opening capillary structures for drug transport screening assays
The blood-brain barrier (BBB), a selective barrier regulating the active and passive transport of solutes in the extracellular fluid of the central nervous system, prevents the delivery of therapeutics for brain disorders. The BBB is composed of brain microvascular endothelial cells (BMEC), pericyte...
Autores principales: | Piantino, Marie, Kang, Dong-Hee, Furihata, Tomomi, Nakatani, Noriyuki, Kitamura, Kimiko, Shigemoto-Mogami, Yukari, Sato, Kaoru, Matsusaki, Michiya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214798/ https://www.ncbi.nlm.nih.gov/pubmed/35757028 http://dx.doi.org/10.1016/j.mtbio.2022.100324 |
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