Assembly checkpoint of the proteasome regulatory particle is activated by coordinated actions of proteasomal ATPase chaperones

The proteasome holoenzyme regulates the cellular proteome via degrading most proteins. In its 19-subunit regulatory particle (RP), a heterohexameric ATPase enables protein degradation by injecting protein substrates into the core peptidase. RP assembly utilizes “checkpoints,” where multiple dedicate...

Descripción completa

Detalles Bibliográficos
Autores principales: Nahar, Asrafun, Sokolova, Vladyslava, Sekaran, Suganya, Orth, James D., Park, Soyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214829/
https://www.ncbi.nlm.nih.gov/pubmed/35675778
http://dx.doi.org/10.1016/j.celrep.2022.110918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214829/
https://www.ncbi.nlm.nih.gov/pubmed/35675778
http://dx.doi.org/10.1016/j.celrep.2022.110918

Ejemplares similares