Cargando…

Construction of a quaternary stereogenic center by asymmetric hydroformylation: a straightforward method to prepare chiral α-quaternary amino acids

The construction of chiral quaternary carbon stereocenters has been a long-standing challenge in organic chemistry. Particularly, α-quaternary amino acids that are of high importance in biochemistry still lack a straightforward synthetic method. We here reported a hydroformylation approach to access...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Dequan, Wen, Jialin, Zhang, Xumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214857/
https://www.ncbi.nlm.nih.gov/pubmed/35799829
http://dx.doi.org/10.1039/d2sc02139k