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Ultrafast and selective labeling of endogenous proteins using affinity-based benzotriazole chemistry

Chemical modification of proteins is enormously useful for characterizing protein function in complex biological systems and for drug development. Selective labeling of native or endogenous proteins is challenging owing to the existence of distinct functional groups in proteins and in living systems...

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Detalles Bibliográficos
Autores principales: Xin, Xiaoyi, Zhang, Yu, Gaetani, Massimiliano, Lundström, Susanna L., Zubarev, Roman A., Zhou, Yuan, Corkery, Dale P., Wu, Yao-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214888/
https://www.ncbi.nlm.nih.gov/pubmed/35799822
http://dx.doi.org/10.1039/d1sc05974b