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Enantioselective iodolactonization to prepare ε-lactone rings using hypervalent iodine

Despite the rapid growth of enantioselective halolactonization reactions in recent years, most are effective only when forming smaller (6,5,4-membered) rings. Seven-membered ε-lactones, are rarely formed with high selectivity, and never without conformational bias. We describe the first highly enant...

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Detalles Bibliográficos
Autores principales: Payne, Jenna L., Deng, Zihang, Flach, Andrew L., Johnston, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214890/
https://www.ncbi.nlm.nih.gov/pubmed/35799806
http://dx.doi.org/10.1039/d2sc01587k