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GSTP1 c.313A > G mutation is an independent risk factor for neutropenia hematotoxicity induced by anthracycline-/paclitaxel-based chemotherapy in breast cancer patients

BACKGROUND: The link between glutathione S-transferase P1 (GSTP1) c.313A > G polymorphism and chemotherapy-related adverse events remains controversial. The goal of this study was to assess how this variant affected the toxicity of anthracycline-/paclitaxel-based chemotherapy in patients with bre...

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Detalles Bibliográficos
Autores principales: Zeng, Juanzi, Wu, Heming, Liu, Donghua, Li, Liang, Li, Jiaquan, Wang, Qiuming, Ye, Min, Huang, Qingyan, Yu, Zhikang, Zhang, Jinfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214976/
https://www.ncbi.nlm.nih.gov/pubmed/35729577
http://dx.doi.org/10.1186/s12957-022-02679-y