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High levels of TDO2 in relation to pro-inflammatory cytokines in synovium and synovial fluid of patients with osteoarthritis

BACKGROUND: Tryptophan 2,3-dioxygenase (TDO2) is the primary enzyme that catabolizes tryptophan to kynurenine. Numerous studies have suggested that TDO2 is involved in inflammation-related diseases. However, its role in osteoarthritis (OA) has not yet been investigated. The aim of the present study...

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Detalles Bibliográficos
Autores principales:	Rong, Genxiang, Zhang, Tao, Xu, Yayun, Zhang, Zhenyu, Gui, Binjie, Hu, Kongzu, Zhang, Jinling, Tang, Zhi, Shen, Cailiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214984/ https://www.ncbi.nlm.nih.gov/pubmed/35733134 http://dx.doi.org/10.1186/s12891-022-05567-4

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