Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells

BACKGROUND: Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of pancreas (UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had poorly described histopathological and clinical features. METHODS: In this study, single-cell RNA sequencing (scRNA-seq) was use...

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Detalles Bibliográficos
Autores principales: Wang, Xinbo, Miao, Jiaying, Wang, Sizhen, Shen, Rongxi, Zhang, Shuo, Tian, Yurao, Li, Min, Zhu, Daojun, Yao, Anlong, Bao, Wei, Zhang, Qun, Tang, Xingming, Wang, Xingyun, Li, Jieshou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214989/
https://www.ncbi.nlm.nih.gov/pubmed/35733218
http://dx.doi.org/10.1186/s12943-022-01596-8

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