Repression of HIV-1 reactivation mediated by CRISPR/dCas9-KRAB in lymphoid and myeloid cell models

BACKGROUND: Despite antiretroviral treatment efficacy, it does not lead to the complete eradication of HIV infection. Consequently, reactivation of the virus from latently infected cell reservoirs is a major challenge toward cure efforts. Two strategies targeting viral latency are currently under in...

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Detalles Bibliográficos
Autores principales: da Costa, Lendel Correia, Bomfim, Larissa Maciel, Dittz, Uilla Victoria Torres, Velozo, Camila de Almeida, da Cunha, Rodrigo Delvecchio, Tanuri, Amilcar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215058/
https://www.ncbi.nlm.nih.gov/pubmed/35733180
http://dx.doi.org/10.1186/s12977-022-00600-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215058/
https://www.ncbi.nlm.nih.gov/pubmed/35733180
http://dx.doi.org/10.1186/s12977-022-00600-9

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