Pyridine appended 2-hydrazinylthiazole derivatives: design, synthesis, in vitro and in silico antimycobacterial studies

An array of pyridine appended 2-hydrazinylthiazole derivatives has been synthesized to discover novel chemotherapeutic agents for Mycobacterium tuberculosis (Mtb). The drug-likeness of pyridine appended 2-hydrazinylthiazole derivatives was validated using the Lipinski and Veber rules. The designed t...

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Detalles Bibliográficos
Autores principales: Matsa, Ramkishore, Makam, Parameshwar, Sethi, Guneswar, Thottasseri, Ahammed Ameen, Kizhakkandiyil, Aswani Raj, Ramadas, Krishna, Mariappan, Vignesh, Pillai, Agieshkumar Balakrishna, Kannan, Tharanikkarasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215125/
https://www.ncbi.nlm.nih.gov/pubmed/35799934
http://dx.doi.org/10.1039/d2ra02163c

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