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Lung function and exercise capacity 6 months after hospital discharge for critical COVID-19

BACKGROUND: The significant morbidity caused by COVID-19 necessitates further understanding of long-term recovery. Our aim was to evaluate long-term lung function, exercise capacity, and radiological findings in patients after critical COVID-19. METHODS: Patients who received treatment in ICU for CO...

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Autores principales: Kattainen, Salla, Lindahl, Anna, Vasankari, Tuula, Ollila, Henriikka, Volmonen, Kirsi, Piirilä, Päivi, Kauppi, Paula, Paajanen, Juuso, Kreivi, Hanna-Riikka, Ulenius, Linda, Varpula, Tero, Aro, Miia, Reijula, Jere, Hästbacka, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215155/
https://www.ncbi.nlm.nih.gov/pubmed/35733179
http://dx.doi.org/10.1186/s12890-022-02023-w
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author Kattainen, Salla
Lindahl, Anna
Vasankari, Tuula
Ollila, Henriikka
Volmonen, Kirsi
Piirilä, Päivi
Kauppi, Paula
Paajanen, Juuso
Kreivi, Hanna-Riikka
Ulenius, Linda
Varpula, Tero
Aro, Miia
Reijula, Jere
Hästbacka, Johanna
author_facet Kattainen, Salla
Lindahl, Anna
Vasankari, Tuula
Ollila, Henriikka
Volmonen, Kirsi
Piirilä, Päivi
Kauppi, Paula
Paajanen, Juuso
Kreivi, Hanna-Riikka
Ulenius, Linda
Varpula, Tero
Aro, Miia
Reijula, Jere
Hästbacka, Johanna
author_sort Kattainen, Salla
collection PubMed
description BACKGROUND: The significant morbidity caused by COVID-19 necessitates further understanding of long-term recovery. Our aim was to evaluate long-term lung function, exercise capacity, and radiological findings in patients after critical COVID-19. METHODS: Patients who received treatment in ICU for COVID-19 between March 2020 and January 2021 underwent pulmonary function tests, a 6MWD and CXR 6 months after hospital discharge. RESULTS: A restrictive ventilatory defect was found in 35% (23/65) and an impaired diffusing capacity in 52% (32/62) at 6 months. The 6-minute walk distance was reduced in 33% (18/55), and 7% (4/55) of the patients had reduced exercise capacity. Chest X-ray was abnormal in 78% (52/67) at 6 months after hospital discharge. CONCLUSION: A significant number of patients had persisting lung function impairment and radiological abnormalities at 6 months after critical COVID-19. Reduced exercise capacity was rare. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12890-022-02023-w.
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spelling pubmed-92151552022-06-22 Lung function and exercise capacity 6 months after hospital discharge for critical COVID-19 Kattainen, Salla Lindahl, Anna Vasankari, Tuula Ollila, Henriikka Volmonen, Kirsi Piirilä, Päivi Kauppi, Paula Paajanen, Juuso Kreivi, Hanna-Riikka Ulenius, Linda Varpula, Tero Aro, Miia Reijula, Jere Hästbacka, Johanna BMC Pulm Med Research BACKGROUND: The significant morbidity caused by COVID-19 necessitates further understanding of long-term recovery. Our aim was to evaluate long-term lung function, exercise capacity, and radiological findings in patients after critical COVID-19. METHODS: Patients who received treatment in ICU for COVID-19 between March 2020 and January 2021 underwent pulmonary function tests, a 6MWD and CXR 6 months after hospital discharge. RESULTS: A restrictive ventilatory defect was found in 35% (23/65) and an impaired diffusing capacity in 52% (32/62) at 6 months. The 6-minute walk distance was reduced in 33% (18/55), and 7% (4/55) of the patients had reduced exercise capacity. Chest X-ray was abnormal in 78% (52/67) at 6 months after hospital discharge. CONCLUSION: A significant number of patients had persisting lung function impairment and radiological abnormalities at 6 months after critical COVID-19. Reduced exercise capacity was rare. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12890-022-02023-w. BioMed Central 2022-06-22 /pmc/articles/PMC9215155/ /pubmed/35733179 http://dx.doi.org/10.1186/s12890-022-02023-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Kattainen, Salla
Lindahl, Anna
Vasankari, Tuula
Ollila, Henriikka
Volmonen, Kirsi
Piirilä, Päivi
Kauppi, Paula
Paajanen, Juuso
Kreivi, Hanna-Riikka
Ulenius, Linda
Varpula, Tero
Aro, Miia
Reijula, Jere
Hästbacka, Johanna
Lung function and exercise capacity 6 months after hospital discharge for critical COVID-19
title Lung function and exercise capacity 6 months after hospital discharge for critical COVID-19
title_full Lung function and exercise capacity 6 months after hospital discharge for critical COVID-19
title_fullStr Lung function and exercise capacity 6 months after hospital discharge for critical COVID-19
title_full_unstemmed Lung function and exercise capacity 6 months after hospital discharge for critical COVID-19
title_short Lung function and exercise capacity 6 months after hospital discharge for critical COVID-19
title_sort lung function and exercise capacity 6 months after hospital discharge for critical covid-19
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215155/
https://www.ncbi.nlm.nih.gov/pubmed/35733179
http://dx.doi.org/10.1186/s12890-022-02023-w
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