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Target-induced activation of DNAzyme for highly sensitive colorimetric detection of bleomycin via DNA scission

In this work, a label-free and sensitive colorimetric sensing strategy for the detection of bleomycin (BLM) was developed on the basis of BLM-mediated activation of G-quadruplex DNAzyme via DNA strand scission. A G-quadruplex based hairpin probe (G4HP) containing the scission site (5′-GT-3′) of BLM...

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Detalles Bibliográficos
Autores principales: Liao, Xiaofei, Li, Mengyan, Zou, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215162/
https://www.ncbi.nlm.nih.gov/pubmed/35799941
http://dx.doi.org/10.1039/d2ra02816f