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Eosinophilic Granulomatosis with Polyangiitis
Eosinophilic granulomatosis with polyangiitis also known as Churg–Strauss syndrome or allergic granulomatosis and angiitis is an extremely rare systemic necrotizing vasculitis that affects small-to-medium-sized vessels. Here, we report a case of a 58-year-old man presenting with painful swelling of...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215177/ https://www.ncbi.nlm.nih.gov/pubmed/35754674 http://dx.doi.org/10.4103/ijabmr.ijabmr_528_21 |
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author | Shukla, Ratnakar Kandikatla, Ashwini Nadkarni, Nitin J Patil, Anant |
author_facet | Shukla, Ratnakar Kandikatla, Ashwini Nadkarni, Nitin J Patil, Anant |
author_sort | Shukla, Ratnakar |
collection | PubMed |
description | Eosinophilic granulomatosis with polyangiitis also known as Churg–Strauss syndrome or allergic granulomatosis and angiitis is an extremely rare systemic necrotizing vasculitis that affects small-to-medium-sized vessels. Here, we report a case of a 58-year-old man presenting with painful swelling of bilateral lower limbs with multiple well-defined erosions on lower legs and dorsum of the foot with a few of them showing brownish crusts and with slight watery discharge and a few with raw areas. The patient is a known case of bronchial asthma. Histopathology of foot and face lesion shows inflammatory cell infiltrate predominantly comprising of eosinophils, small- and medium-sized blood vessels are thickened. P-antineutrophil cytoplasmic antibody positivity was seen. Thus, on the basis of positive findings which satisfy the criteria for eosinophilic granulomatosis with polyangiitis, we diagnosed this as a case of eosinophilic granulomatosis with polyangiitis, and for rarity of this case, we would like to report it. |
format | Online Article Text |
id | pubmed-9215177 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-92151772022-06-23 Eosinophilic Granulomatosis with Polyangiitis Shukla, Ratnakar Kandikatla, Ashwini Nadkarni, Nitin J Patil, Anant Int J Appl Basic Med Res Case Report Eosinophilic granulomatosis with polyangiitis also known as Churg–Strauss syndrome or allergic granulomatosis and angiitis is an extremely rare systemic necrotizing vasculitis that affects small-to-medium-sized vessels. Here, we report a case of a 58-year-old man presenting with painful swelling of bilateral lower limbs with multiple well-defined erosions on lower legs and dorsum of the foot with a few of them showing brownish crusts and with slight watery discharge and a few with raw areas. The patient is a known case of bronchial asthma. Histopathology of foot and face lesion shows inflammatory cell infiltrate predominantly comprising of eosinophils, small- and medium-sized blood vessels are thickened. P-antineutrophil cytoplasmic antibody positivity was seen. Thus, on the basis of positive findings which satisfy the criteria for eosinophilic granulomatosis with polyangiitis, we diagnosed this as a case of eosinophilic granulomatosis with polyangiitis, and for rarity of this case, we would like to report it. Wolters Kluwer - Medknow 2022 2022-05-10 /pmc/articles/PMC9215177/ /pubmed/35754674 http://dx.doi.org/10.4103/ijabmr.ijabmr_528_21 Text en Copyright: © 2022 International Journal of Applied and Basic Medical Research https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Shukla, Ratnakar Kandikatla, Ashwini Nadkarni, Nitin J Patil, Anant Eosinophilic Granulomatosis with Polyangiitis |
title | Eosinophilic Granulomatosis with Polyangiitis |
title_full | Eosinophilic Granulomatosis with Polyangiitis |
title_fullStr | Eosinophilic Granulomatosis with Polyangiitis |
title_full_unstemmed | Eosinophilic Granulomatosis with Polyangiitis |
title_short | Eosinophilic Granulomatosis with Polyangiitis |
title_sort | eosinophilic granulomatosis with polyangiitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215177/ https://www.ncbi.nlm.nih.gov/pubmed/35754674 http://dx.doi.org/10.4103/ijabmr.ijabmr_528_21 |
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