Cargando…

Eosinophilic Granulomatosis with Polyangiitis

Eosinophilic granulomatosis with polyangiitis also known as Churg–Strauss syndrome or allergic granulomatosis and angiitis is an extremely rare systemic necrotizing vasculitis that affects small-to-medium-sized vessels. Here, we report a case of a 58-year-old man presenting with painful swelling of...

Descripción completa

Detalles Bibliográficos
Autores principales: Shukla, Ratnakar, Kandikatla, Ashwini, Nadkarni, Nitin J, Patil, Anant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215177/
https://www.ncbi.nlm.nih.gov/pubmed/35754674
http://dx.doi.org/10.4103/ijabmr.ijabmr_528_21
_version_ 1784731158541500416
author Shukla, Ratnakar
Kandikatla, Ashwini
Nadkarni, Nitin J
Patil, Anant
author_facet Shukla, Ratnakar
Kandikatla, Ashwini
Nadkarni, Nitin J
Patil, Anant
author_sort Shukla, Ratnakar
collection PubMed
description Eosinophilic granulomatosis with polyangiitis also known as Churg–Strauss syndrome or allergic granulomatosis and angiitis is an extremely rare systemic necrotizing vasculitis that affects small-to-medium-sized vessels. Here, we report a case of a 58-year-old man presenting with painful swelling of bilateral lower limbs with multiple well-defined erosions on lower legs and dorsum of the foot with a few of them showing brownish crusts and with slight watery discharge and a few with raw areas. The patient is a known case of bronchial asthma. Histopathology of foot and face lesion shows inflammatory cell infiltrate predominantly comprising of eosinophils, small- and medium-sized blood vessels are thickened. P-antineutrophil cytoplasmic antibody positivity was seen. Thus, on the basis of positive findings which satisfy the criteria for eosinophilic granulomatosis with polyangiitis, we diagnosed this as a case of eosinophilic granulomatosis with polyangiitis, and for rarity of this case, we would like to report it.
format Online
Article
Text
id pubmed-9215177
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-92151772022-06-23 Eosinophilic Granulomatosis with Polyangiitis Shukla, Ratnakar Kandikatla, Ashwini Nadkarni, Nitin J Patil, Anant Int J Appl Basic Med Res Case Report Eosinophilic granulomatosis with polyangiitis also known as Churg–Strauss syndrome or allergic granulomatosis and angiitis is an extremely rare systemic necrotizing vasculitis that affects small-to-medium-sized vessels. Here, we report a case of a 58-year-old man presenting with painful swelling of bilateral lower limbs with multiple well-defined erosions on lower legs and dorsum of the foot with a few of them showing brownish crusts and with slight watery discharge and a few with raw areas. The patient is a known case of bronchial asthma. Histopathology of foot and face lesion shows inflammatory cell infiltrate predominantly comprising of eosinophils, small- and medium-sized blood vessels are thickened. P-antineutrophil cytoplasmic antibody positivity was seen. Thus, on the basis of positive findings which satisfy the criteria for eosinophilic granulomatosis with polyangiitis, we diagnosed this as a case of eosinophilic granulomatosis with polyangiitis, and for rarity of this case, we would like to report it. Wolters Kluwer - Medknow 2022 2022-05-10 /pmc/articles/PMC9215177/ /pubmed/35754674 http://dx.doi.org/10.4103/ijabmr.ijabmr_528_21 Text en Copyright: © 2022 International Journal of Applied and Basic Medical Research https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Shukla, Ratnakar
Kandikatla, Ashwini
Nadkarni, Nitin J
Patil, Anant
Eosinophilic Granulomatosis with Polyangiitis
title Eosinophilic Granulomatosis with Polyangiitis
title_full Eosinophilic Granulomatosis with Polyangiitis
title_fullStr Eosinophilic Granulomatosis with Polyangiitis
title_full_unstemmed Eosinophilic Granulomatosis with Polyangiitis
title_short Eosinophilic Granulomatosis with Polyangiitis
title_sort eosinophilic granulomatosis with polyangiitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215177/
https://www.ncbi.nlm.nih.gov/pubmed/35754674
http://dx.doi.org/10.4103/ijabmr.ijabmr_528_21
work_keys_str_mv AT shuklaratnakar eosinophilicgranulomatosiswithpolyangiitis
AT kandikatlaashwini eosinophilicgranulomatosiswithpolyangiitis
AT nadkarninitinj eosinophilicgranulomatosiswithpolyangiitis
AT patilanant eosinophilicgranulomatosiswithpolyangiitis