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Gastrointestinal tuberculosis presenting as acute abdomen: a case report

Intestinal tuberculosis (ITB) represents an important diagnostic challenge in the clinical setting, as it generally can occur as a chronic condition often mimicking other diseases such as Crohn’s disease (CD), and can present itself with acute onset, which can be life-threatening. A 29-years-old Chi...

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Autores principales: Ridolfo, Sofia, Cammarata, Francesco, Bonomi, Alessandro M, Troci, Albert, Crespi, Michele, Molteni, Paola, Pellegrinelli, Alessandro, Ardizzone, Sandro, Danelli, Piergiorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215354/
https://www.ncbi.nlm.nih.gov/pubmed/35755016
http://dx.doi.org/10.1093/jscr/rjac305
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author Ridolfo, Sofia
Cammarata, Francesco
Bonomi, Alessandro M
Troci, Albert
Crespi, Michele
Molteni, Paola
Pellegrinelli, Alessandro
Ardizzone, Sandro
Danelli, Piergiorgio
author_facet Ridolfo, Sofia
Cammarata, Francesco
Bonomi, Alessandro M
Troci, Albert
Crespi, Michele
Molteni, Paola
Pellegrinelli, Alessandro
Ardizzone, Sandro
Danelli, Piergiorgio
author_sort Ridolfo, Sofia
collection PubMed
description Intestinal tuberculosis (ITB) represents an important diagnostic challenge in the clinical setting, as it generally can occur as a chronic condition often mimicking other diseases such as Crohn’s disease (CD), and can present itself with acute onset, which can be life-threatening. A 29-years-old Chinese woman coming to ER with abdominal pain, fever and weight loss. Computed tomography and colonoscopy images were not diagnostic. Despite medical therapy, the patient progressively worsened developing sepsis requiring emergency surgery. Pathological and microbiological examination of the colon both pointed towards gastrointestinal tuberculosis involvement. Although ITB is generally a chronic-wasting condition, it can also occur as acute abdomen representing an absolute surgical emergency. Although caseation and necrosis in granulomas can be used for diagnosis of ITB, preoperative diagnosis is still challenging. Endoscopic biopsies targeted to ulcerous lesions could be an essential diagnostic tool, contrary to those targeted to the ulcers’ edges as performed in CD.
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spelling pubmed-92153542022-06-23 Gastrointestinal tuberculosis presenting as acute abdomen: a case report Ridolfo, Sofia Cammarata, Francesco Bonomi, Alessandro M Troci, Albert Crespi, Michele Molteni, Paola Pellegrinelli, Alessandro Ardizzone, Sandro Danelli, Piergiorgio J Surg Case Rep Case Report Intestinal tuberculosis (ITB) represents an important diagnostic challenge in the clinical setting, as it generally can occur as a chronic condition often mimicking other diseases such as Crohn’s disease (CD), and can present itself with acute onset, which can be life-threatening. A 29-years-old Chinese woman coming to ER with abdominal pain, fever and weight loss. Computed tomography and colonoscopy images were not diagnostic. Despite medical therapy, the patient progressively worsened developing sepsis requiring emergency surgery. Pathological and microbiological examination of the colon both pointed towards gastrointestinal tuberculosis involvement. Although ITB is generally a chronic-wasting condition, it can also occur as acute abdomen representing an absolute surgical emergency. Although caseation and necrosis in granulomas can be used for diagnosis of ITB, preoperative diagnosis is still challenging. Endoscopic biopsies targeted to ulcerous lesions could be an essential diagnostic tool, contrary to those targeted to the ulcers’ edges as performed in CD. Oxford University Press 2022-06-21 /pmc/articles/PMC9215354/ /pubmed/35755016 http://dx.doi.org/10.1093/jscr/rjac305 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2022. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Ridolfo, Sofia
Cammarata, Francesco
Bonomi, Alessandro M
Troci, Albert
Crespi, Michele
Molteni, Paola
Pellegrinelli, Alessandro
Ardizzone, Sandro
Danelli, Piergiorgio
Gastrointestinal tuberculosis presenting as acute abdomen: a case report
title Gastrointestinal tuberculosis presenting as acute abdomen: a case report
title_full Gastrointestinal tuberculosis presenting as acute abdomen: a case report
title_fullStr Gastrointestinal tuberculosis presenting as acute abdomen: a case report
title_full_unstemmed Gastrointestinal tuberculosis presenting as acute abdomen: a case report
title_short Gastrointestinal tuberculosis presenting as acute abdomen: a case report
title_sort gastrointestinal tuberculosis presenting as acute abdomen: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215354/
https://www.ncbi.nlm.nih.gov/pubmed/35755016
http://dx.doi.org/10.1093/jscr/rjac305
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