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A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide

Since the beginning of the COVID-19 pandemic, there has been an increased need for the development of novel diagnostic solutions that can accurately and rapidly detect SARS-CoV-2 infection. In this work, we demonstrate the targeting of viral oligonucleotide markers within minutes without the require...

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Detalles Bibliográficos
Autores principales: Alexaki, Konstantina, Kyriazi, Maria Eleni, Greening, Joshua, Taemaitree, Lapatrada, El-Sagheer, Afaf H., Brown, Tom, Zhang, Xunli, Muskens, Otto L., Kanaras, Antonios G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215703/
https://www.ncbi.nlm.nih.gov/pubmed/35799935
http://dx.doi.org/10.1039/d2ra03599e
Descripción
Sumario:Since the beginning of the COVID-19 pandemic, there has been an increased need for the development of novel diagnostic solutions that can accurately and rapidly detect SARS-CoV-2 infection. In this work, we demonstrate the targeting of viral oligonucleotide markers within minutes without the requirement of a polymerase chain reaction (PCR) amplification step via the use of oligonucleotide-coated upconversion nanoparticles (UCNPs) and graphene oxide (GO).