A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide

Since the beginning of the COVID-19 pandemic, there has been an increased need for the development of novel diagnostic solutions that can accurately and rapidly detect SARS-CoV-2 infection. In this work, we demonstrate the targeting of viral oligonucleotide markers within minutes without the require...

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Autores principales: Alexaki, Konstantina, Kyriazi, Maria Eleni, Greening, Joshua, Taemaitree, Lapatrada, El-Sagheer, Afaf H., Brown, Tom, Zhang, Xunli, Muskens, Otto L., Kanaras, Antonios G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215703/
https://www.ncbi.nlm.nih.gov/pubmed/35799935
http://dx.doi.org/10.1039/d2ra03599e
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author Alexaki, Konstantina
Kyriazi, Maria Eleni
Greening, Joshua
Taemaitree, Lapatrada
El-Sagheer, Afaf H.
Brown, Tom
Zhang, Xunli
Muskens, Otto L.
Kanaras, Antonios G.
author_facet Alexaki, Konstantina
Kyriazi, Maria Eleni
Greening, Joshua
Taemaitree, Lapatrada
El-Sagheer, Afaf H.
Brown, Tom
Zhang, Xunli
Muskens, Otto L.
Kanaras, Antonios G.
author_sort Alexaki, Konstantina
collection PubMed
description Since the beginning of the COVID-19 pandemic, there has been an increased need for the development of novel diagnostic solutions that can accurately and rapidly detect SARS-CoV-2 infection. In this work, we demonstrate the targeting of viral oligonucleotide markers within minutes without the requirement of a polymerase chain reaction (PCR) amplification step via the use of oligonucleotide-coated upconversion nanoparticles (UCNPs) and graphene oxide (GO).
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spelling pubmed-92157032022-07-06 A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide Alexaki, Konstantina Kyriazi, Maria Eleni Greening, Joshua Taemaitree, Lapatrada El-Sagheer, Afaf H. Brown, Tom Zhang, Xunli Muskens, Otto L. Kanaras, Antonios G. RSC Adv Chemistry Since the beginning of the COVID-19 pandemic, there has been an increased need for the development of novel diagnostic solutions that can accurately and rapidly detect SARS-CoV-2 infection. In this work, we demonstrate the targeting of viral oligonucleotide markers within minutes without the requirement of a polymerase chain reaction (PCR) amplification step via the use of oligonucleotide-coated upconversion nanoparticles (UCNPs) and graphene oxide (GO). The Royal Society of Chemistry 2022-06-22 /pmc/articles/PMC9215703/ /pubmed/35799935 http://dx.doi.org/10.1039/d2ra03599e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Alexaki, Konstantina
Kyriazi, Maria Eleni
Greening, Joshua
Taemaitree, Lapatrada
El-Sagheer, Afaf H.
Brown, Tom
Zhang, Xunli
Muskens, Otto L.
Kanaras, Antonios G.
A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide
title A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide
title_full A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide
title_fullStr A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide
title_full_unstemmed A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide
title_short A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide
title_sort sars-cov-2 sensor based on upconversion nanoparticles and graphene oxide
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215703/
https://www.ncbi.nlm.nih.gov/pubmed/35799935
http://dx.doi.org/10.1039/d2ra03599e
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