Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease

Abnormal hematopoiesis advances cardiovascular disease by generating excess inflammatory leukocytes that attack the arteries and the heart. The bone marrow niche regulates hematopoietic stem cell proliferation and hence the systemic leukocyte pool, but whether cardiovascular disease affects the hema...

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Detalles Bibliográficos
Autores principales: Rohde, David, Vandoorne, Katrien, Lee, I-Hsiu, Grune, Jana, Zhang, Shuang, McAlpine, Cameron S., Schloss, Maximilian J., Nayar, Ribhu, Courties, Gabriel, Frodermann, Vanessa, Wojtkiewicz, Gregory, Honold, Lisa, Chen, Qi, Schmidt, Stephen, Iwamoto, Yoshiko, Sun, Yuan, Cremer, Sebastian, Hoyer, Friedrich F., Iborra-Egea, Oriol, Muñoz-Guijosa, Christian, Ji, Fei, Zhou, Bin, Adams, Ralf H., Wythe, Joshua D., Hidalgo, Juan, Watanabe, Hideto, Jung, Yookyung, van der Laan, Anja M., Piek, Jan J., Kfoury, Youmna, Désogère, Pauline A., Vinegoni, Claudio, Dutta, Partha, Sadreyev, Ruslan I., Caravan, Peter, Bayes-Genis, Antoni, Libby, Peter, Scadden, David T., Lin, Charles P., Naxerova, Kamila, Swirski, Filip K., Nahrendorf, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216333/
https://www.ncbi.nlm.nih.gov/pubmed/35747128
http://dx.doi.org/10.1038/s44161-021-00002-8

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