Gene editing: Towards the third generation of adoptive T-cell transfer therapies

First-generation adoptive T-cell transfer (ACT) administering tumor-infiltrating lymphocytes (TILs), and second-generation ACT using autologous T cells genetically modified to express tumor-specific T-cell receptors (TCRs) or chimeric antigen receptors (CARs) have both shown promise for the treatmen...

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Detalles Bibliográficos
Autores principales: Puig-Saus, Cristina, Ribas, Antoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216344/
https://www.ncbi.nlm.nih.gov/pubmed/35755321
http://dx.doi.org/10.1016/j.iotech.2019.06.001

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