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AnthraxKP: a knowledge graph-based, Anthrax Knowledge Portal mined from biomedical literature

Anthrax is a zoonotic infectious disease caused by Bacillus anthracis (anthrax bacterium) that affects not only domestic and wild animals worldwide but also human health. As the study develops in-depth, a large quantity of related biomedical publications emerge. Acquiring knowledge from the literatu...

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Detalles Bibliográficos
Autores principales: Feng, Baiyang, Gao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216567/
https://www.ncbi.nlm.nih.gov/pubmed/35653350
http://dx.doi.org/10.1093/database/baac037
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author Feng, Baiyang
Gao, Jing
author_facet Feng, Baiyang
Gao, Jing
author_sort Feng, Baiyang
collection PubMed
description Anthrax is a zoonotic infectious disease caused by Bacillus anthracis (anthrax bacterium) that affects not only domestic and wild animals worldwide but also human health. As the study develops in-depth, a large quantity of related biomedical publications emerge. Acquiring knowledge from the literature is essential for gaining insight into anthrax etiology, diagnosis, treatment and research. In this study, we used a set of text mining tools to identify nearly 14 000 entities of 29 categories, such as genes, diseases, chemicals, species, vaccines and proteins, from nearly 8000 anthrax biomedical literature and extracted 281 categories of association relationships among the entities. We curated Anthrax-related Entities Dictionary and Anthrax Ontology. We formed Anthrax Knowledge Graph (AnthraxKG) containing more than 6000 nodes, 6000 edges and 32 000 properties. An interactive visualized Anthrax Knowledge Portal(AnthraxKP) was also developed based on AnthraxKG by using Web technology. AnthraxKP in this study provides rich and authentic relevant knowledge in many forms, which can help researchers carry out research more efficiently. Database URL: AnthraxKP is permitted users to query and download data at http://139.224.212.120:18095/.
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spelling pubmed-92165672022-06-23 AnthraxKP: a knowledge graph-based, Anthrax Knowledge Portal mined from biomedical literature Feng, Baiyang Gao, Jing Database (Oxford) Original Article Anthrax is a zoonotic infectious disease caused by Bacillus anthracis (anthrax bacterium) that affects not only domestic and wild animals worldwide but also human health. As the study develops in-depth, a large quantity of related biomedical publications emerge. Acquiring knowledge from the literature is essential for gaining insight into anthrax etiology, diagnosis, treatment and research. In this study, we used a set of text mining tools to identify nearly 14 000 entities of 29 categories, such as genes, diseases, chemicals, species, vaccines and proteins, from nearly 8000 anthrax biomedical literature and extracted 281 categories of association relationships among the entities. We curated Anthrax-related Entities Dictionary and Anthrax Ontology. We formed Anthrax Knowledge Graph (AnthraxKG) containing more than 6000 nodes, 6000 edges and 32 000 properties. An interactive visualized Anthrax Knowledge Portal(AnthraxKP) was also developed based on AnthraxKG by using Web technology. AnthraxKP in this study provides rich and authentic relevant knowledge in many forms, which can help researchers carry out research more efficiently. Database URL: AnthraxKP is permitted users to query and download data at http://139.224.212.120:18095/. Oxford University Press 2022-06-02 /pmc/articles/PMC9216567/ /pubmed/35653350 http://dx.doi.org/10.1093/database/baac037 Text en © The Author(s) 2022. Published by Oxford University Press. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Article
Feng, Baiyang
Gao, Jing
AnthraxKP: a knowledge graph-based, Anthrax Knowledge Portal mined from biomedical literature
title AnthraxKP: a knowledge graph-based, Anthrax Knowledge Portal mined from biomedical literature
title_full AnthraxKP: a knowledge graph-based, Anthrax Knowledge Portal mined from biomedical literature
title_fullStr AnthraxKP: a knowledge graph-based, Anthrax Knowledge Portal mined from biomedical literature
title_full_unstemmed AnthraxKP: a knowledge graph-based, Anthrax Knowledge Portal mined from biomedical literature
title_short AnthraxKP: a knowledge graph-based, Anthrax Knowledge Portal mined from biomedical literature
title_sort anthraxkp: a knowledge graph-based, anthrax knowledge portal mined from biomedical literature
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216567/
https://www.ncbi.nlm.nih.gov/pubmed/35653350
http://dx.doi.org/10.1093/database/baac037
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