A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice

Powassan virus (POWV) is an emerging tick borne flavivirus (TBFV) that causes severe neuroinvasive disease. Currently, there are no approved treatments or vaccines to combat POWV infection. Here, we generated and characterized a nanoparticle immunogen displaying domain III (EDIII) of the POWV E glyc...

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Detalles Bibliográficos
Autores principales: Malonis, Ryan J., Georgiev, George I., Haslwanter, Denise, VanBlargan, Laura A., Fallon, Georgia, Vergnolle, Olivia, Cahill, Sean M., Harris, Richard, Cowburn, David, Chandran, Kartik, Diamond, Michael S., Lai, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216602/
https://www.ncbi.nlm.nih.gov/pubmed/35679349
http://dx.doi.org/10.1371/journal.ppat.1010573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216602/
https://www.ncbi.nlm.nih.gov/pubmed/35679349
http://dx.doi.org/10.1371/journal.ppat.1010573

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