Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes

The adenylate cyclase (ACT) and the pertussis (PT) toxins of Bordetella pertussis exert potent immunomodulatory activities that synergize to suppress host defense in the course of whooping cough pathogenesis. We compared the mouse lung infection capacities of B. pertussis (Bp) mutants (Bp AC(−) or B...

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Detalles Bibliográficos
Autores principales: Klimova, Nela, Holubova, Jana, Streparola, Gaia, Tomala, Jakub, Brazdilova, Ludmila, Stanek, Ondrej, Bumba, Ladislav, Sebo, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216613/
https://www.ncbi.nlm.nih.gov/pubmed/35666769
http://dx.doi.org/10.1371/journal.ppat.1010577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216613/
https://www.ncbi.nlm.nih.gov/pubmed/35666769
http://dx.doi.org/10.1371/journal.ppat.1010577

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