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Pertussis toxin suppresses dendritic cell-mediated delivery of B. pertussis into lung-draining lymph nodes
The adenylate cyclase (ACT) and the pertussis (PT) toxins of Bordetella pertussis exert potent immunomodulatory activities that synergize to suppress host defense in the course of whooping cough pathogenesis. We compared the mouse lung infection capacities of B. pertussis (Bp) mutants (Bp AC(−) or B...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216613/ https://www.ncbi.nlm.nih.gov/pubmed/35666769 http://dx.doi.org/10.1371/journal.ppat.1010577 |