Cargando…

The (re)discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens

Functional genetic screens by CRISPR-Cas9 allow for the unbiased discovery of proteins causally involved in complex biological processes. In recent years, this approach has been used by multiple laboratories to uncover a range of tumor cell regulators determining immune sensitivity. In this review,...

Descripción completa

Detalles Bibliográficos
Autores principales: Vredevoogd, D.W., Apriamashvili, G., Peeper, D.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216628/
https://www.ncbi.nlm.nih.gov/pubmed/35756970
http://dx.doi.org/10.1016/j.iotech.2021.100043