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The (re)discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens
Functional genetic screens by CRISPR-Cas9 allow for the unbiased discovery of proteins causally involved in complex biological processes. In recent years, this approach has been used by multiple laboratories to uncover a range of tumor cell regulators determining immune sensitivity. In this review,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216628/ https://www.ncbi.nlm.nih.gov/pubmed/35756970 http://dx.doi.org/10.1016/j.iotech.2021.100043 |