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Empirical Model of Spring 2020 Decrease in Daily Confirmed COVID-19 Cases in King County, Washington

Projections of the near future of daily case incidence of COVID-19 are valuable for informing public policy. Near-future estimates are also useful for outbreaks of other diseases. Short-term predictions are unlikely to be affected by changes in herd immunity. In the absence of major net changes in f...

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Detalles Bibliográficos
Autor principal: Roach, Jared C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216716/
https://www.ncbi.nlm.nih.gov/pubmed/35734092
http://dx.doi.org/10.1101/2020.05.11.20098798
Descripción
Sumario:Projections of the near future of daily case incidence of COVID-19 are valuable for informing public policy. Near-future estimates are also useful for outbreaks of other diseases. Short-term predictions are unlikely to be affected by changes in herd immunity. In the absence of major net changes in factors that affect reproduction number (R), the two-parameter exponential model should be a standard model – indeed, it has been standard for epidemiological analysis of pandemics for a century but in recent decades has lost popularity to more complex compartmental models. Exponential models should be routinely included in reports describing epidemiological models as a reference, or null hypothesis. Exponential models should be fitted separately for each epidemiologically distinct jurisdiction. They should also be fitted separately to time intervals that differ by any major changes in factors that affect R. Using an exponential model, incidence-count half-life (t(1/2)) is a better statistic than R. Here an example of the exponential model is applied to King County, Washington during Spring 2020. During the pandemic, the parameters and predictions of this model have remained stable for intervals of one to four months, and the accuracy of model predictions has outperformed models with more parameters. The COVID pandemic can be modeled as a series of exponential curves, each spanning an interval ranging from one to four months. The length of these intervals is hard to predict, other than to extrapolate that future intervals will last about as long as past intervals.