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SARS-CoV-2 infection of human brain microvascular endothelial cells leads to inflammatory activation through NF-κB non-canonical pathway and mitochondrial remodeling

Neurological effects of COVID-19 and long-COVID-19 as well as neuroinvasion by SARS-CoV-2 still pose several questions and are of both clinical and scientific relevance. We described the cellular and molecular effects of the human brain microvascular endothelial cells (HBMECs) in vitro infection by...

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Detalles Bibliográficos
Autores principales: Torices, Silvia, Motta, Carolline Soares, da Rosa, Barbara Gomes, Marcos, Anne Caroline, Alvarez-Rosa, Liandra, Siqueira, Michele, Moreno-Rodriguez, Thaidy, Matos, Aline, Caetano, Braulia, Martins, Jessica, Gladulich, Luis, Loiola, Erick, Bagshaw, Olivia RM, Stuart, Jeffrey A., Siqueira, Marilda M., Stipursky, Joice, Toborek, Michal, Adesse, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216721/
https://www.ncbi.nlm.nih.gov/pubmed/35734080
http://dx.doi.org/10.1101/2022.06.16.496324