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Preclinical platforms to study therapeutic efficacy of human γδ T cells

BACKGROUND: Gamma delta (γδ) T lymphocytes are promising candidate for adoptive T cell therapy, however, their treatment efficacy is not satisfactory. Vδ2 T cells are unique to primates and few suitable models are available to assay their anti‐tumour function. METHODS: We tested human γδ T cell acti...

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Detalles Bibliográficos
Autores principales: Ou, Lingling, Wang, Huaishan, Huang, Hui, Zhou, Zhiyan, Lin, Qiang, Guo, Yeye, Mitchell, Tara, Huang, Alexander C., Karakousis, Giorgos, Schuchter, Lynn, Amaravadi, Ravi, Guo, Wei, Salvino, Joseph, Herlyn, Meenhard, Xu, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217106/
https://www.ncbi.nlm.nih.gov/pubmed/35731974
http://dx.doi.org/10.1002/ctm2.814