Characterization of the RNA-dependent RNA polymerase from Chikungunya virus and discovery of a novel ligand as a potential drug candidate

Chikungunya virus (CHIKV) is the causative agent of Chikungunya fever, an acute febrile and arthritogenic illness with no effective treatments available. The development of effective therapeutic strategies could be significantly accelerated with detailed knowledge of the molecular components behind...

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Detalles Bibliográficos
Autores principales: Freire, Marjorie C. L. C., Basso, Luis G. M., Mendes, Luis F. S., Mesquita, Nathalya C. M. R., Mottin, Melina, Fernandes, Rafaela S., Policastro, Lucca R., Godoy, Andre S., Santos, Igor A., Ruiz, Uriel E. A., Caruso, Icaro P., Sousa, Bruna K. P., Jardim, Ana C. G., Almeida, Fabio C. L., Gil, Laura H. V. G., Andrade, Carolina H., Oliva, Glaucius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217121/
https://www.ncbi.nlm.nih.gov/pubmed/35732685
http://dx.doi.org/10.1038/s41598-022-14790-x

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