Altered excitatory and inhibitory neuronal subpopulation parameters are distinctly associated with tau and amyloid in Alzheimer’s disease

BACKGROUND: Neuronal- and circuit-level abnormalities of excitation and inhibition are shown to be associated with tau and amyloid-beta (Aβ) in preclinical models of Alzheimer’s disease (AD). These relationships remain poorly understood in patients with AD. METHODS: Using empirical spectra from magn...

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Detalles Bibliográficos
Autores principales: Ranasinghe, Kamalini G, Verma, Parul, Cai, Chang, Xie, Xihe, Kudo, Kiwamu, Gao, Xiao, Lerner, Hannah, Mizuiri, Danielle, Strom, Amelia, Iaccarino, Leonardo, La Joie, Renaud, Miller, Bruce L, Gorno-Tempini, Maria Luisa, Rankin, Katherine P, Jagust, William J, Vossel, Keith, Rabinovici, Gil D, Raj, Ashish, Nagarajan, Srikantan S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217132/
https://www.ncbi.nlm.nih.gov/pubmed/35616532
http://dx.doi.org/10.7554/eLife.77850

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