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TOPK Affects Autophagy of Skin Squamous Cell Carcinoma by Regulating NF-KB Pathway through HDAC1

OBJECTIVE: To explore the effect and potential mechanism of T-LAK cell-originated protein kinase (TOPK) on autophagy in cutaneous squamous cell carcinoma (cSCC). METHODS: Human cSCC cancer tissue and paracancerous tissue samples were collected clinically; immunohistochemistry was used to detect the...

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Detalles Bibliográficos
Autores principales: Li, Juan, Zhang, Zhi-chao, Yuan, Xiang-shi, Tang, Shan-shan, Wang, Tao, Liu, Hong-fu, Cao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217538/
https://www.ncbi.nlm.nih.gov/pubmed/35756488
http://dx.doi.org/10.1155/2022/3771711