Cargando…
TOPK Affects Autophagy of Skin Squamous Cell Carcinoma by Regulating NF-KB Pathway through HDAC1
OBJECTIVE: To explore the effect and potential mechanism of T-LAK cell-originated protein kinase (TOPK) on autophagy in cutaneous squamous cell carcinoma (cSCC). METHODS: Human cSCC cancer tissue and paracancerous tissue samples were collected clinically; immunohistochemistry was used to detect the...
Autores principales: | Li, Juan, Zhang, Zhi-chao, Yuan, Xiang-shi, Tang, Shan-shan, Wang, Tao, Liu, Hong-fu, Cao, Yu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217538/ https://www.ncbi.nlm.nih.gov/pubmed/35756488 http://dx.doi.org/10.1155/2022/3771711 |
Ejemplares similares
-
Targeting PRPK and TOPK for skin cancer prevention and therapy
por: Roh, Eunmiri, et al.
Publicado: (2018) -
TOPK Promotes Microglia/Macrophage Polarization towards M2 Phenotype via Inhibition of HDAC1 and HDAC2 Activity after Transient Cerebral Ischemia
por: Han, Ziping, et al.
Publicado: (2018) -
Comprehensive Physicochemical Characterization, In Vitro Membrane Permeation, and In Vitro Human Skin Cell Culture of a Novel TOPK Inhibitor, HI-TOPK-032
por: Eedara, Basanth Babu, et al.
Publicado: (2023) -
TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ
por: Lu, Hui, et al.
Publicado: (2019) -
IMMU-19. HDAC INHIBITORS SENSITIZE MYC-AMPLIFIED MEDULLOBLASTOMA TO IMMUNOTHERAPY BY ACTIVATING THE NF-kB PATHWAYS
por: Marquardt, Viktoria, et al.
Publicado: (2020)