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Poricoic Acid A Inhibits the NF-κB/MAPK Pathway to Alleviate Renal Fibrosis in Rats with Cardiorenal Syndrome

OBJECTIVE: To explore the potential and mechanism of action of poricoic acid A (PAA) in treatment of cardiorenal injury and fibrosis due to cardiorenal syndrome (CRS). MATERIALS AND METHODS: A CRS rat model was established by transabdominal subtotal nephrectomy (STNx). The experimental group was tre...

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Detalles Bibliográficos
Autores principales: Chen, Wenzhong, Fan, Zhiwen, Huang, Canhui, Liu, Junying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217574/
https://www.ncbi.nlm.nih.gov/pubmed/35754696
http://dx.doi.org/10.1155/2022/8644353