Cargando…

Poricoic Acid A Inhibits the NF-κB/MAPK Pathway to Alleviate Renal Fibrosis in Rats with Cardiorenal Syndrome

OBJECTIVE: To explore the potential and mechanism of action of poricoic acid A (PAA) in treatment of cardiorenal injury and fibrosis due to cardiorenal syndrome (CRS). MATERIALS AND METHODS: A CRS rat model was established by transabdominal subtotal nephrectomy (STNx). The experimental group was tre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Wenzhong, Fan, Zhiwen, Huang, Canhui, Liu, Junying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217574/ https://www.ncbi.nlm.nih.gov/pubmed/35754696 http://dx.doi.org/10.1155/2022/8644353

Ejemplares similares

Retracted: Poricoic Acid A Inhibits the NF-κB/MAPK Pathway to Alleviate Renal Fibrosis in Rats with Cardiorenal Syndrome
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Poricoic acid A suppresses TGF-β1-induced renal fibrosis and proliferation via the PDGF-C, Smad3 and MAPK pathways
por: Li, Qiang, et al.
Publicado: (2021)

Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum
por: Chen, Dan-Qian, et al.
Publicado: (2019)

Mindin deficiency alleviates renal fibrosis through inhibiting NF‐κB and TGF‐β/Smad pathways
por: Yang, Kang, et al.
Publicado: (2020)

Combination of Niclosamide and Pirfenidone Alleviates Pulmonary Fibrosis by Inhibiting Oxidative Stress and MAPK/Nf-κB and STATs Regulated Genes
por: Wanas, Hanaa, et al.
Publicado: (2023)

Salidroside Ameliorates Renal Interstitial Fibrosis by Inhibiting the TLR4/NF-κB and MAPK Signaling Pathways
por: Li, Rui, et al.
Publicado: (2019)

Poricoic acid A suppresses renal fibroblast activation and interstitial fibrosis in UUO rats via upregulating Sirt3 and promoting β-catenin K49 deacetylation
por: Chen, Dan-Qian, et al.
Publicado: (2022)

Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis via modulating protein stability of β-catenin and β-catenin-mediated transcription
por: Chen, Dan-Qian, et al.
Publicado: (2020)

Enhanced-Dose Statins for ST-Segment Elevation Myocardial Infarction Patients after Emergency Percutaneous Coronary Intervention
por: Chen, Wenzhong, et al.
Publicado: (2022)

Rapeseed protein-derived antioxidant peptide RAP alleviates renal fibrosis through MAPK/NF-κB signaling pathways in diabetic nephropathy
por: Zhang, Mingyan, et al.
Publicado: (2018)

(-)-α-Bisabolol Alleviates Atopic Dermatitis by Inhibiting MAPK and NF-κB Signaling in Mast Cell
por: Li, Guangxia, et al.
Publicado: (2022)

Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways
por: Li, Baixing, et al.
Publicado: (2022)

Roxatidine inhibits fibrosis by inhibiting NF-κB and MAPK signaling in macrophages sensing breast implant surface materials
por: Ji, Litong, et al.
Publicado: (2020)

Tamarixinin A Alleviates Joint Destruction of Rheumatoid Arthritis by Blockade of MAPK and NF-κB Activation
por: Zhuang, Yuanyuan, et al.
Publicado: (2017)

Rosmanol and Carnosol Synergistically Alleviate Rheumatoid Arthritis through Inhibiting TLR4/NF-κB/MAPK Pathway
por: Li, Lianchun, et al.
Publicado: (2021)

Perivascular radiofrequency renal denervation lowers blood pressure and ameliorates cardiorenal fibrosis in spontaneously hypertensive rats
por: Wei, Shujie, et al.
Publicado: (2017)

Huangjia Ruangan Granule Inhibits Inflammation in a Rat Model with Liver Fibrosis by Regulating TNF/MAPK and NF-κB Signaling Pathways
por: Cai, Qiang, et al.
Publicado: (2022)

The Extracts of Dendrobium Alleviate Dry Eye Disease in Rat Model by Regulating Aquaporin Expression and MAPKs/NF-κB Signalling
por: Ling, Jiawei, et al.
Publicado: (2022)

4-Acetylantroquinonol B inhibits lipopolysaccharide-induced cytokine release and alleviates sepsis through of MAPK and NFκB suppression
por: Chang, Chien-Hsin, et al.
Publicado: (2018)

Adiporedoxin suppresses endothelial activation via inhibiting MAPK and NF-κB signaling
por: He, Hui, et al.
Publicado: (2016)

Inhibition of the NF-κB Signaling Pathway Alleviates Pyroptosis in Bladder Epithelial Cells and Neurogenic Bladder Fibrosis
por: Chen, Jing, et al.
Publicado: (2023)

Hydrogen sulfide ameliorates chronic renal failure in rats by inhibiting apoptosis and inflammation through ROS/MAPK and NF-κB signaling pathways
por: Wu, Dongdong, et al.
Publicado: (2017)

Curcumin Alleviates oxLDL Induced MMP-9 and EMMPRIN Expression through the Inhibition of NF-κB and MAPK Pathways in Macrophages
por: Cao, Jiatian, et al.
Publicado: (2017)

Xanthatin Alleviates LPS-Induced Inflammatory Response in RAW264.7 Macrophages by Inhibiting NF-κB, MAPK and STATs Activation
por: Liu, Yuanqi, et al.
Publicado: (2022)

Downregulation of cathepsin C alleviates endothelial cell dysfunction by suppressing p38 MAPK/NF-κB pathway in preeclampsia
por: Lu, Fan, et al.
Publicado: (2022)

TXNIP/TRX/NF-κB and MAPK/NF-κB pathways involved in the cardiotoxicity induced by Venenum Bufonis in rats
por: Bi, Qi-rui, et al.
Publicado: (2016)

Rhein alleviates renal interstitial fibrosis by inhibiting tubular cell apoptosis in rats
por: Chen, Yakun, et al.
Publicado: (2019)

Heidihuangwan alleviates renal fibrosis in rats with 5/6 nephrectomy by inhibiting autophagy
por: Li, Ying-Ying, et al.
Publicado: (2022)

Apoptosis signal-regulating kinase 1 inhibition attenuates cardiac hypertrophy and cardiorenal fibrosis induced by uremic toxins: Implications for cardiorenal syndrome
por: Savira, Feby, et al.
Publicado: (2017)

D-Limonene mitigate myocardial injury in rats through MAPK/ERK/NF-κB pathway inhibition
por: Younis, Nancy Safwat
Publicado: (2020)

Rhein inhibits malignant phenotypes of human renal cell carcinoma by impacting on MAPK/NF-κB signaling pathways
por: Ma, Ya-Li, et al.
Publicado: (2018)

Artemisinin inhibits monocyte adhesion to HUVECs through the NF-κB and MAPK pathways in vitro
por: WANG, YUE, et al.
Publicado: (2016)

Ginsenoside Rg1 treatment alleviates renal fibrosis by inhibiting the NOX4–MAPK pathway in T2DM mice
por: Ji, Pengmin, et al.
Publicado: (2023)

TNFAIP3 alleviates pain in lumbar disc herniation rats by inhibiting the NF-κB pathway
por: Xie, Zhaohui, et al.
Publicado: (2022)

The SUMOylation of TAB2 mediated by TRIM60 inhibits MAPK/NF-κB activation and the innate immune response
por: Gu, Zhiwen, et al.
Publicado: (2020)

Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-κB and MAPK pathways
por: Chen, Yan, et al.
Publicado: (2018)

Dihydroartemisinin attenuates osteoclast formation and bone resorption via inhibiting the NF-κB, MAPK and NFATc1 signaling pathways and alleviates osteoarthritis
por: Ding, Dong, et al.
Publicado: (2022)

Ulinastatin alleviates early brain injury after intracerebral hemorrhage by inhibiting necroptosis and neuroinflammation via MAPK/NF-κB signaling pathway
por: Wang, Li, et al.
Publicado: (2022)

Renal Assessment in Acute Cardiorenal Syndrome
por: Łagosz, Piotr, et al.
Publicado: (2023)

Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
por: Zhang, Kun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sek13e1ql3sljdebmfec31si7a