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A randomised, open-label, cross-over clinical study to evaluate the pharmacokinetic, pharmacodynamic and safety and tolerability profiles of tobacco-free oral nicotine pouches relative to cigarettes
RATIONALE: Tobacco harm reduction (THR) involves encouraging adult smokers who would otherwise continue to smoke to transition to less harmful forms of nicotine delivery. These products must offer adult smokers reduced exposure to chemicals associated with tobacco combustion, satisfactory blood plas...
Autores principales: | Chapman, Fiona, McDermott, Simon, Rudd, Kathryn, Taverner, Victoria, Stevenson, Matthew, Chaudhary, Nveed, Reichmann, Kerstin, Thompson, Joseph, Nahde, Thomas, O’Connell, Grant |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217727/ https://www.ncbi.nlm.nih.gov/pubmed/35732751 http://dx.doi.org/10.1007/s00213-022-06178-6 |
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