RNase III-CLASH of multi-drug resistant Staphylococcus aureus reveals a regulatory mRNA 3′UTR required for intermediate vancomycin resistance

Treatment of methicillin-resistant Staphylococcus aureus infections is dependent on the efficacy of last-line antibiotics including vancomycin. Treatment failure is commonly linked to isolates with intermediate vancomycin resistance (termed VISA). These isolates have accumulated point mutations that...

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Detalles Bibliográficos
Autores principales: Mediati, Daniel G., Wong, Julia L., Gao, Wei, McKellar, Stuart, Pang, Chi Nam Ignatius, Wu, Sylvania, Wu, Winton, Sy, Brandon, Monk, Ian R., Biazik, Joanna M., Wilkins, Marc R., Howden, Benjamin P., Stinear, Timothy P., Granneman, Sander, Tree, Jai J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217812/
https://www.ncbi.nlm.nih.gov/pubmed/35732665
http://dx.doi.org/10.1038/s41467-022-31177-8

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