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Alzheimer disease neuropathology in a patient previously treated with aducanumab
Amyloid beta (Aβ) plaque is a defining pathologic feature of Alzheimer disease (AD). Aducanumab, a monoclonal IgG1 that selectively binds aggregated species of Aβ, has been shown by amyloid positron emission tomography (Amyloid PET) to reduce Aβ plaques in patients with prodromal and mild AD. This i...
Autores principales: | Plowey, Edward D., Bussiere, Thierry, Rajagovindan, Raj, Sebalusky, Jennifer, Hamann, Stefan, von Hehn, Christian, Castrillo-Viguera, Carmen, Sandrock, Alfred, Budd Haeberlein, Samantha, van Dyck, Christopher H., Huttner, Anita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217863/ https://www.ncbi.nlm.nih.gov/pubmed/35581440 http://dx.doi.org/10.1007/s00401-022-02433-4 |
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