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Factors associated with mortality in older patients sustaining pelvic or acetabular fractures

INTRODUCTION: This study aimed to investigate potential factors, including delay to surgical stabilisation, affecting mortality in older patients sustaining pelvic or acetabular (PA) fractures. MATERIALS AND METHODS: A retrospective review of the Trauma Audit and Research Network (TARN) database was...

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Autores principales: Harrison, Anna, Ordas-Bayon, Alejandro, Chimutengwende-Gordon, Mukai, Fortune, Mary, Chou, Daud, Hull, Peter, Carrothers, Andrew, Rawal, Jaikirty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217874/
https://www.ncbi.nlm.nih.gov/pubmed/33813616
http://dx.doi.org/10.1007/s00402-021-03873-5
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author Harrison, Anna
Ordas-Bayon, Alejandro
Chimutengwende-Gordon, Mukai
Fortune, Mary
Chou, Daud
Hull, Peter
Carrothers, Andrew
Rawal, Jaikirty
author_facet Harrison, Anna
Ordas-Bayon, Alejandro
Chimutengwende-Gordon, Mukai
Fortune, Mary
Chou, Daud
Hull, Peter
Carrothers, Andrew
Rawal, Jaikirty
author_sort Harrison, Anna
collection PubMed
description INTRODUCTION: This study aimed to investigate potential factors, including delay to surgical stabilisation, affecting mortality in older patients sustaining pelvic or acetabular (PA) fractures. MATERIALS AND METHODS: A retrospective review of the Trauma Audit and Research Network (TARN) database was performed to identify older patients (aged 65 and over) sustaining PA fractures treated surgically in a UK Major Trauma Centre (MTC) between 2015 and 2019. Chi-squared and Fisher tests were used to compare 1-year mortality rates following operative intervention between patients treated within 72 h and after 72 h. Kaplan–Meier curves were used to visualise survival probability; significant predictors of survival were found using Cox proportional hazard models. RESULTS: Of 564 older patients with PA fractures, 70 met the inclusion criteria. The mean age was 76.1 years. The overall 1-year mortality rate was 20%. When patients were grouped by time to surgery (fracture fixation within or greater than 72 h), there was no statistically significant difference in 1-year mortality. Patients whose surgery was delayed more than 72 h were more likely to have longer hospital stays (p = 0.002) or to have suffered from polytrauma (p = 0.025). Age, Charlson Co-morbidities Index (CCI) and pre-op mobility status were associated with statistically significant differences in overall mortality. The same factors were associated with a significantly increased hazard of death in the multivariate Cox proportional hazards model. Patient gender, mechanism of injury, Injury Severity Score (ISS) > 15 and head injury were not significant predictors of mortality. CONCLUSION: Surgical intervention within 72 h of injury did not result in decreased mortality in older patients with PA fractures. The 1-year mortality rate between older PA fractures and hip fractures was comparable. Consideration should be given to a combined multidisciplinary approach between orthogeriatric and expert PA surgeons for these patients.
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spelling pubmed-92178742022-06-24 Factors associated with mortality in older patients sustaining pelvic or acetabular fractures Harrison, Anna Ordas-Bayon, Alejandro Chimutengwende-Gordon, Mukai Fortune, Mary Chou, Daud Hull, Peter Carrothers, Andrew Rawal, Jaikirty Arch Orthop Trauma Surg Trauma Surgery INTRODUCTION: This study aimed to investigate potential factors, including delay to surgical stabilisation, affecting mortality in older patients sustaining pelvic or acetabular (PA) fractures. MATERIALS AND METHODS: A retrospective review of the Trauma Audit and Research Network (TARN) database was performed to identify older patients (aged 65 and over) sustaining PA fractures treated surgically in a UK Major Trauma Centre (MTC) between 2015 and 2019. Chi-squared and Fisher tests were used to compare 1-year mortality rates following operative intervention between patients treated within 72 h and after 72 h. Kaplan–Meier curves were used to visualise survival probability; significant predictors of survival were found using Cox proportional hazard models. RESULTS: Of 564 older patients with PA fractures, 70 met the inclusion criteria. The mean age was 76.1 years. The overall 1-year mortality rate was 20%. When patients were grouped by time to surgery (fracture fixation within or greater than 72 h), there was no statistically significant difference in 1-year mortality. Patients whose surgery was delayed more than 72 h were more likely to have longer hospital stays (p = 0.002) or to have suffered from polytrauma (p = 0.025). Age, Charlson Co-morbidities Index (CCI) and pre-op mobility status were associated with statistically significant differences in overall mortality. The same factors were associated with a significantly increased hazard of death in the multivariate Cox proportional hazards model. Patient gender, mechanism of injury, Injury Severity Score (ISS) > 15 and head injury were not significant predictors of mortality. CONCLUSION: Surgical intervention within 72 h of injury did not result in decreased mortality in older patients with PA fractures. The 1-year mortality rate between older PA fractures and hip fractures was comparable. Consideration should be given to a combined multidisciplinary approach between orthogeriatric and expert PA surgeons for these patients. Springer Berlin Heidelberg 2021-04-03 2022 /pmc/articles/PMC9217874/ /pubmed/33813616 http://dx.doi.org/10.1007/s00402-021-03873-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Trauma Surgery
Harrison, Anna
Ordas-Bayon, Alejandro
Chimutengwende-Gordon, Mukai
Fortune, Mary
Chou, Daud
Hull, Peter
Carrothers, Andrew
Rawal, Jaikirty
Factors associated with mortality in older patients sustaining pelvic or acetabular fractures
title Factors associated with mortality in older patients sustaining pelvic or acetabular fractures
title_full Factors associated with mortality in older patients sustaining pelvic or acetabular fractures
title_fullStr Factors associated with mortality in older patients sustaining pelvic or acetabular fractures
title_full_unstemmed Factors associated with mortality in older patients sustaining pelvic or acetabular fractures
title_short Factors associated with mortality in older patients sustaining pelvic or acetabular fractures
title_sort factors associated with mortality in older patients sustaining pelvic or acetabular fractures
topic Trauma Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217874/
https://www.ncbi.nlm.nih.gov/pubmed/33813616
http://dx.doi.org/10.1007/s00402-021-03873-5
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