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Screening of commonly prescribed drugs for effects on the CAT1-mediated transport of l-arginine and arginine derivatives
The cationic amino acid transporter 1 (CAT1/SLC7A1) plays a key role in the cellular uptake or export of l-arginine and some of its derivatives. This study investigated the effect of 113 chemically diverse and commonly used drugs (at 20 and 200 µM) on the CAT1-mediated cellular uptake of l-arginine,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Vienna
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217908/ https://www.ncbi.nlm.nih.gov/pubmed/35377022 http://dx.doi.org/10.1007/s00726-022-03156-2 |