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Barriers to Chimeric Antigen Receptor T-Cell (CAR-T) Therapies in Clinical Practice

Chimeric antigen receptor T-cell (CAR-T) therapy is a revolutionary cancer treatment modality where a patient’s own T cells are collected and engineered ex vivo to express a chimeric antigen receptor (CAR). These reprogrammed CAR-T cells, when reinfused into the same patient, stimulate a T-cell medi...

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Detalles Bibliográficos
Autores principales: Gajra, Ajeet, Zalenski, Abigail, Sannareddy, Aishwarya, Jeune-Smith, Yolaine, Kapinos, Kandice, Kansagra, Ankit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217916/
https://www.ncbi.nlm.nih.gov/pubmed/35672571
http://dx.doi.org/10.1007/s40290-022-00428-w