SIN-3 functions through multi-protein interaction to regulate apoptosis, autophagy, and longevity in Caenorhabditis elegans

SIN3/HDAC is a multi-protein complex that acts as a regulatory unit and functions as a co-repressor/co-activator and a general transcription factor. SIN3 acts as a scaffold in the complex, binding directly to HDAC1/2 and other proteins and plays crucial roles in regulating apoptosis, differentiation...

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Detalles Bibliográficos
Autores principales: Konwar, Chandrika, Maini, Jayant, Kohli, Surbhi, Brahmachari, Vani, Saluja, Daman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217932/
https://www.ncbi.nlm.nih.gov/pubmed/35732652
http://dx.doi.org/10.1038/s41598-022-13864-0

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