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Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival

The random-pattern skin flap is a crucial technique in reconstructive surgery and flap necrosis caused by ischemia/reperfusion injury is a major postoperative complication. Herein, we investigated the mechanism of mitophagy induced by Melatonin (ML) and its effect on the survival of skin flaps. Our...

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Detalles Bibliográficos
Autores principales:	Chen, Zhengtai, Wu, Hongqiang, Yang, Jianxin, Li, Baolong, Ding, Jian, Cheng, Sheng, Bsoul, Nageeb, Zhang, Chenxi, li, jiaorong, Liu, Haixiao, Lin, Damu, Gao, Weiyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217959/ https://www.ncbi.nlm.nih.gov/pubmed/35732814 http://dx.doi.org/10.1038/s42003-022-03556-w

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