Nanobody-based retargeting of an oncolytic herpesvirus for eliminating CXCR4(+) GBM cells: A proof of principle

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, which remains difficult to cure. The very high recurrence rate has been partly attributed to the presence of GBM stem-like cells (GSCs) within the tumors, which have been associated with elevated chemokine receptor 4 (CXCR4) ex...

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Detalles Bibliográficos
Autores principales: Sanchez Gil, Judit, Dubois, Maxime, Neirinckx, Virginie, Lombard, Arnaud, Coppieters, Natacha, D’Arrigo, Paolo, Isci, Damla, Aldenhoff, Therese, Brouwers, Benoit, Lassence, Cédric, Rogister, Bernard, Lebrun, Marielle, Sadzot-Delvaux, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9217993/
https://www.ncbi.nlm.nih.gov/pubmed/35784400
http://dx.doi.org/10.1016/j.omto.2022.06.002

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