Cargando…
Circ_0000705 facilitates proline metabolism of esophageal squamous cell carcinoma cells by targeting miR-621/PYCR1 axis
CircRNAs have been found to play crucial roles in the metabolism and progression of cancers, but their roles and mechanisms in esophageal squamous cell carcinoma (ESCC) have not been fully elucidated. This work is aimed to explore the role and mechanism of hsa_circ_0000705 (circ_0000705) in ESCC. Ci...
Autores principales: | Qian, Cui-juan, Tong, Yi-yang, Wu, Lin-ken, Wang, Yi-chao, Teng, Xiao-sheng, Yao, Jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218025/ https://www.ncbi.nlm.nih.gov/pubmed/35731336 http://dx.doi.org/10.1007/s12672-022-00513-1 |
Ejemplares similares
-
In crystallo screening for proline analog inhibitors of the proline cycle enzyme PYCR1
por: Christensen, Emily M., et al.
Publicado: (2021) -
SIRT3 regulates cancer cell proliferation through deacetylation of PYCR1 in proline metabolism()
por: Chen, Shuaiyi, et al.
Publicado: (2019) -
Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions
por: Westbrook, Rebecca L., et al.
Publicado: (2022) -
Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
por: Kay, Emily J., et al.
Publicado: (2022) -
Targeting PYCR2 inhibits intraperitoneal metastatic tumors of mouse colorectal cancer in a proline‐independent approach
por: Zhang, Qi, et al.
Publicado: (2022)