An Overview of Alphafold's Breakthrough

This paper presents a short summary of the protein folding problem, what it is and why it is significant. Introduces the CASP competition and how accuracy is measured. Looks at different approaches for solving the problem followed by a review of the current breakthroughs in the field introduced by A...

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Detalles Bibliográficos
Autores principales: Marcu, Ştefan-Bogdan, Tăbîrcă, Sabin, Tangney, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Artificial Intelligence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218062/
https://www.ncbi.nlm.nih.gov/pubmed/35757294
http://dx.doi.org/10.3389/frai.2022.875587
Descripción
Sumario:This paper presents a short summary of the protein folding problem, what it is and why it is significant. Introduces the CASP competition and how accuracy is measured. Looks at different approaches for solving the problem followed by a review of the current breakthroughs in the field introduced by AlphaFold 1 and AlphaFold 2.

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