An Overview of Alphafold's Breakthrough

This paper presents a short summary of the protein folding problem, what it is and why it is significant. Introduces the CASP competition and how accuracy is measured. Looks at different approaches for solving the problem followed by a review of the current breakthroughs in the field introduced by A...

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Detalles Bibliográficos
Autores principales: Marcu, Ştefan-Bogdan, Tăbîrcă, Sabin, Tangney, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Artificial Intelligence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218062/
https://www.ncbi.nlm.nih.gov/pubmed/35757294
http://dx.doi.org/10.3389/frai.2022.875587
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author Marcu, Ştefan-Bogdan
Tăbîrcă, Sabin
Tangney, Mark
author_facet Marcu, Ştefan-Bogdan
Tăbîrcă, Sabin
Tangney, Mark
author_sort Marcu, Ştefan-Bogdan
collection PubMed
description This paper presents a short summary of the protein folding problem, what it is and why it is significant. Introduces the CASP competition and how accuracy is measured. Looks at different approaches for solving the problem followed by a review of the current breakthroughs in the field introduced by AlphaFold 1 and AlphaFold 2.
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spelling pubmed-92180622022-06-24 An Overview of Alphafold's Breakthrough Marcu, Ştefan-Bogdan Tăbîrcă, Sabin Tangney, Mark Front Artif Intell Artificial Intelligence This paper presents a short summary of the protein folding problem, what it is and why it is significant. Introduces the CASP competition and how accuracy is measured. Looks at different approaches for solving the problem followed by a review of the current breakthroughs in the field introduced by AlphaFold 1 and AlphaFold 2. Frontiers Media S.A. 2022-06-09 /pmc/articles/PMC9218062/ /pubmed/35757294 http://dx.doi.org/10.3389/frai.2022.875587 Text en Copyright © 2022 Marcu, Tăbîrcă and Tangney. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Artificial Intelligence
Marcu, Ştefan-Bogdan
Tăbîrcă, Sabin
Tangney, Mark
An Overview of Alphafold's Breakthrough
title An Overview of Alphafold's Breakthrough
title_full An Overview of Alphafold's Breakthrough
title_fullStr An Overview of Alphafold's Breakthrough
title_full_unstemmed An Overview of Alphafold's Breakthrough
title_short An Overview of Alphafold's Breakthrough
title_sort overview of alphafold's breakthrough
topic Artificial Intelligence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218062/
https://www.ncbi.nlm.nih.gov/pubmed/35757294
http://dx.doi.org/10.3389/frai.2022.875587
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