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ACT001 Inhibits TLR4 Signaling by Targeting Co-Receptor MD2 and Attenuates Neuropathic Pain

Neuropathic pain is a common and challenging neurological disease, which renders an unmet need for safe and effective new therapies. Toll-like receptor 4 (TLR4) expressed on immune cells in the central nervous system arises as a novel target for treating neuropathic pain. In this study, ACT001, an o...

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Detalles Bibliográficos
Autores principales:	Zhang, Tianshu, Lin, Cong, Wu, Siru, Jin, Sha, Li, Xiaodong, Peng, Yinghua, Wang, Xiaohui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218074/ https://www.ncbi.nlm.nih.gov/pubmed/35757727 http://dx.doi.org/10.3389/fimmu.2022.873054

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