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The in-silico feasibility of dose escalated, hypofractionated radiotherapy for rectal cancer

BACKGROUND AND PURPOSE: Short course radiotherapy (SCRT) has a low biological prescription dose. Rectal cancer has a dose response relationship and moderate α/β ratio (∼5). We hypothesise hypofractionated dose escalation has radiobiological advantages. We assessed in-silico dose escalation to the pr...

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Detalles Bibliográficos
Autores principales:	Devlin, Lynsey, Grocutt, Laura, Hunter, Bianca, Chemu, Hiwot, Duffton, Aileen, McDonald, Alec, Macleod, Nicholas, McLoone, Philip, O'Cathail, Sean M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9218294/ https://www.ncbi.nlm.nih.gov/pubmed/35756193 http://dx.doi.org/10.1016/j.ctro.2022.06.003

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